This interdisciplinary course will provide the fundamental knowledge for healthcare innovation and entrepreneurship. The course will start with healthcare problem identification, innovative solution design, and eventually pitching the business concept to potential investors. Guest speakers from various schools will provide real-world perspectives and practical knowledge from different angles. Students will be divided into groups and work on either a quality improvement project or a business proposal throughout the 10-week course. There will be a final project presentation at the end of the course. Students are encouraged to later submit the project to annual UChicago app challenge or new venture challenge if applicable.